Head to Settings > Privacy, where you'll see Microphone under App Permission.
Your first port of call should be to check that your microphone has permission to run and that the relevant app can access it. If you've tried all the usual fixes but nothing seems to be working, here are some potential alternative solutions on Windows 10. This is perfectly serviceable most of the time, until it stops functioning altogether.
Unless you've got a solid pair of headphones, you might be relying on your laptop or PC's built-in mic.
With more video calls taking place than ever before, the importance of a reliable microphone has never been greater.